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Quantitative determination of lung water content is important in the study of pulmonary edema, and also for evaluating lung physiology under a variety of conditions. Our implementation of a multi-image gradient echo sequence that collects data at two echo times was shown to produce highly reproducible values of lung density in vivo [1]. This work demonstrated that not only is T2* very short in the lung and varies with lung volume, but T2* must be determined to obtain an accurate measure of quantitative lung density. Although our values of lung density were found to be consistent with previous studies, it is unknown how accurately these values represent absolute water content. The goal of this work was to validate our imaging technique against absolute water content measured gravimetrically using excised pig lungs as a model.