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Sparse‐sampling and reconstruction techniques represent an attractive strategy to achieve faster image acquisition speeds, while maintaining adequate spatial resolution and signal‐to‐noise ratio in rapid magnetic resonance imaging (MRI). The authors investigate the use of one such sequence, broad‐use linear acquisition speed‐up technique (k‐t BLAST) in monitoring tumor motion for thoracic and abdominal radiotherapy and examine the potential trade‐off between increased sparsification (to increase imaging speed) and the potential loss of “true” information due to greater reliance on a priori information.

Lung tumor motion trajectories in the superior–inferior direction, previously recorded from ten lung cancer patients, were replayed using a motion phantom module driven by an MRI‐compatible motion platform. Eppendorf test tubes filled with water which serve as fiducial markers were …