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Disaster is an event that occurs every day which affects a vulnerable population or area; it has dramatic impact on individuals, families and communities. Whether the disaster is a single family house fire or a tsunami that devastates a community, the quality of life is threatened. The aim of this study was to assess the nurses’ perception, attitude and practices regarding disaster management and emergency preparedness, and to find if there is relation between demographic data and their perception, attitude and practice. Cross sectional study design was used in this study. Self administer questionnaire was instructed to collect the data. 150 nurses enrolled in the study which were selected randomly. Data were statistically analyzed by descriptive criteria such as number, percentage, for demographic data, and mean, median and standard deviation for perception, attitude and preventive practices on SPSS version 25 and inferential statistics. Chi square test was used to check the relationship between the variable. The results of this study showed that most of participant nurses have a good knowledge on disaster and its management. And also attitude and practices were good. The conclusion of this study include that nurses perception, attitude and practice were good but, there is no relation between demographic data and their perception, attitude, and practice except experience and level of education with attitude.