作者
Douglas A Corley, Christopher D Jensen, Amy R Marks, Wei K Zhao, Jeffrey K Lee, Chyke A Doubeni, Ann G Zauber, Jolanda De Boer, Bruce H Fireman, Joanne E Schottinger, Virginia P Quinn, Nirupa R Ghai, Theodore R Levin, Charles P Quesenberry
发表日期
2014/4/3
期刊
New england journal of medicine
卷号
370
期号
14
页码范围
1298-1306
出版商
Massachusetts Medical Society
简介
Background
The proportion of screening colonoscopic examinations performed by a physician that detect one or more adenomas (the adenoma detection rate) is a recommended quality measure. However, little is known about the association between this rate and patients' risks of a subsequent colorectal cancer (interval cancer) and death.
Methods
Using data from an integrated health care delivery organization, we evaluated the associations between the adenoma detection rate and the risks of colorectal cancer diagnosed 6 months to 10 years after colonoscopy and of cancer-related death. With the use of Cox regression, our estimates of attributable risk were adjusted for the demographic characteristics of the patients, indications for colonoscopy, and coexisting conditions.
Results
We evaluated 314,872 colonoscopies performed by 136 gastroenterologists; the adenoma detection rates ranged from 7.4 to 52.5 …
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