作者
Gretchen L Sacha, Tyree H Kiser, Garth C Wright, R William Vandivier, Marc Moss, Ellen L Burnham, P Michael Ho, Paul M Reynolds, Seth R Bauer
发表日期
2022/4/1
期刊
Critical Care Medicine
卷号
50
期号
4
页码范围
644-654
出版商
LWW
简介
OBJECTIVES:
Vasopressin is suggested as an adjunct to norepinephrine in patients with septic shock. However, after vasopressin was rebranded in November 2014, its cost exponentially increased. Utilization patterns of vasopressin after its rebranding are unclear. The objective of this study was to determine if there is an association between the rebranding of vasopressin in November 2014 and its utilization in vasopressor-dependent patients with severe sepsis or septic shock.
DESIGN:
Retrospective, multicenter, database study between January 2010 and March 2017.
SETTING:
Premier Healthcare Database hospitals.
PATIENTS:
Adult patients admitted to an ICU with severe sepsis or septic shock, who received at least one vasoactive agent for two or more calendar days were included.
INTERVENTIONS:
The proportion of patients who received vasopressin and vasopressin cost was assessed before and after …
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