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Homogeneity Index (HI) is an objective tool to analyz the uniformity of dose distribution in the target volume. Various formulae have been described in literature for its calculation but there is paucity of data regarding the ideal formula and the factors affecting this index. This study was undertaken to analyze HI in our patients using various formulae and to find out the co-relation between HI and prescribed dose, target volume and target location. A retrospective review of 99 patients was performed. HI was calculated using five different formulae (AE). The patients were divided in five groups each, based on prescribed dose, target volume and target location and mean HI of each group was analysed to find the co-relation between these factors and HI. When there were multiple target volumes the primary target volume was studied. The statistical calculation was done using SPSS version 16.0. Ninety nine patients were …