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Posterior fossa tumors are rare in adults and pose a challenge to treat due to the bony contour of the posterior fossa, complex anatomical structures including deep venous sinuses, and the proximity of the fourth ventricle and brain stem. We describe our experience with laser interstitial thermal therapy (LITT) for the management of brain metastases and radiation necrosis of the posterior fossa.

We retrospectively analyzed 13 patients with metastases and radiation necrosis of the posterior fossa managed with LITT.

Thirteen patients with histopathologically confirmed radiation necrosis (n = 5) and metastases (n = 8) of the posterior fossa underwent LITT. The median preoperative tumor was 4.66 cm³, and median postoperative ablation cavity volume was 6.29 cm³. The median volume of the ablation cavity was decreased to 2.90 cm³ at a 9-month follow-up. The median volume of peritumoral …