作者
Clément Chollat, Emmanuelle Bertrand, Alice Petit-Ledo, Caroline de Vansay, Caroline Voisin, Ivana Dabaj, André Gillibert, Stéphane Marret, C Lévêque, J-L Simenel, S Pauthier, C Levavasseur, I Pop, N Grancher, A Lefebure, C Vittecoq, D Dabbagh, E Machevin, M Levy, F Taleb, H Lahrach, H Rhali, B Richet, F Delaunay, H Bruel, A Selim, M Jaffray, M Durand-Réville, C Sarreau, S Celik, J-F Le Digabel, J Stoller, H Muszynski, M Rouha, E Verspyck, A Chadi, C Lardennois
发表日期
2021/10/1
期刊
The Journal of Pediatrics
卷号
237
页码范围
183-189. e6
出版商
Mosby
简介
Objectives
To describe the prevalence of cerebral palsy (CP) at age 2 years in infants born before 33 weeks of gestation and to analyze the fetal neuroprotective effect of the antenatal administration of magnesium sulfate (MgSO4) treatment on CP.
Study design
Preterm infants born before 33 weeks of gestation and discharged from the Rouen University Hospital's Neonatal Intensive Care Unit between 2007 and 2015 were included. At age 2 years, pediatricians of the perinatal network of Eure and Seine-Maritime counties administered standardized questionnaires analyzing motor, cognitive, and behavioral items, derived from the Denver and Amiel-Tison scales. A routine protocol based on MgSO4 infusion was introduced in 2010. The primary outcome measure was the occurrence of CP according to the Surveillance of Cerebral Palsy in Europe network definition.
Results
A total of 1759 very preterm infants were …
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C Chollat, E Bertrand, A Petit-Ledo, C de Vansay… - The Journal of Pediatrics, 2021