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High-resolution, high-definition colonoscopes (HD) with 170° angle of view providing brighter images, sharper resolution, and a 30° wider field of view than conventional colonoscopes (CC) are available. The impact of these innovations on enhancing the detection of clinically important colonic lesions or over detection of clinically insignificant colonic lesions is not well established.

To compare the difference in the detection of individuals with polyps, adenomas, or high-risk adenoma features between HD and CC. We also compared the difference in detection of individuals with clinically insignificant colonic lesions, ≥2, <6-mm hyperplastic polyps between HD and CC.

Endoscopic findings from 426 individuals who underwent HD were compared to a cohort of 426 individuals who …