作者
Mariana Piana, Mariane Arnoldi Silva, Gabriela Trevisan, Thiele Faccim de Brum, Cássia Regina Silva, Aline Augusti Boligon, Sara Marchesan Oliveira, Marina Zadra, Carin Hoffmeister, Mateus Fortes Rossato, Raquel Tonello, Luciane Varini Laporta, Robson Borba de Freitas, Bianca Vargas Belke, Roberta da Silva Jesus, Juliano Ferreira, Margareth Linde Athayde
发表日期
2013/11/25
期刊
Journal of ethnopharmacology
卷号
150
期号
2
页码范围
458-465
出版商
Elsevier
简介
Ethnopharmacological relevance
Viola tricolor, popularly known as heartsease has been empirically used in several skin disorders, including burns.
Aim of the study
The objective of this study was investigate the antinociceptive and antiinflammatory effect of a gel containing extract of Viola tricolor flowers on thermal burn induced by UVB irradiation and to perform gel stability study.
Methods
The antinociceptive and antiinflammatory effect were evaluated by static and dynamic mechanical allodynia model, paw edema, and neutrophilic cell infiltration. Metabolites compounds were quantified by HPLC. The gel stability study was performed analyzing organoleptical aspects, besides pH, viscosity, and quantification of rutin by HPLC.
Results
In the results were evidenced changes in threshold in statical and dynamic mechanical allodynia (Imax=100±10% and 49±10%, respectively), paw edema (Imax=61±6%), and …
学术搜索中的文章
M Piana, MA Silva, G Trevisan, TF de Brum, CR Silva… - Journal of ethnopharmacology, 2013
