作者
Juliana Vicentini, Juliana Valentini, Denise Grotto, Clóvis Paniz, Miguel Roehrs, Natália Brucker, Mariele F Charão, Angela M Moro, Raquel Tonello, Ana Paula L Moreira, Andréia Buffon, Maristela Beck, Solange Cristina Garcia
发表日期
2011/4
期刊
Journal of Investigative Medicine
卷号
59
期号
4
页码范围
649-654
出版商
SAGE Publications
简介
Aim
Hyperglycemia in diabetes mellitus (DM) may be one of the most important factors responsible for the development of oxidative stress, which promotes the main complications in DM patients. Therefore, this study evaluated if the hyperglycemia could be related to oxidative stress biomarkers, lipid profile, and renal function in type 2 diabetes patients without clinic complications.
Methods
Plasmatic malondialdehyde (MDA), serum protein carbonyl (PCO), serum creatinine levels, microalbuminuria, glycated hemoglobin, and lipid profile were analyzed in 37 type 2 diabetic patients and 25 subjects with no diabetes.
Results
Serum creatinine levels were within the reference values, but microalbuminuria presented increased levels in all the patients compared with controls (P < 0.05) and above of the reference values. The MDA, PCO, low-density lipoprotein, and triglyceride levels showed positive correlation with …
学术搜索中的文章
J Vicentini, J Valentini, D Grotto, C Paniz, M Roehrs… - Journal of Investigative Medicine, 2011
