作者
Jean-Christophe Lagier, Matthieu Million, Philippe Gautret, Philippe Colson, Sébastien Cortaredona, Audrey Giraud-Gatineau, Stéphane Honoré, Jean-Yves Gaubert, Pierre-Edouard Fournier, Hervé Tissot-Dupont, Eric Chabrière, Andreas Stein, Jean-Claude Deharo, Florence Fenollar, Jean-Marc Rolain, Yolande Obadia, Alexis Jacquier, Bernard La Scola, Philippe Brouqui, Michel Drancourt, Philippe Parola, Didier Raoult, Sophie Amrane, Camille Aubry, Matthieu Bardou, Cyril Berenger, Laurence Camoin-Jau, Nadim Cassir, Claire Decoster, Catherine Dhiver, Barbara Doudier, Sophie Edouard, Stéphanie Gentile, Katell Guillon-Lorvellec, Marie Hocquart, Anthony Levasseur, Morgane Mailhe, Isabelle Ravaux, Magali Richez, Yanis Roussel, Piseth Seng, Christelle Tomei, Christine Zandotti
发表日期
2020/7/1
期刊
Travel medicine and infectious disease
卷号
36
页码范围
101791
出版商
Elsevier
简介
Background
In our institute in Marseille, France, we initiated early and massive screening for coronavirus disease 2019 (COVID-19). Hospitalization and early treatment with hydroxychloroquine and azithromycin (HCQ-AZ) was proposed for the positive cases.
Methods
We retrospectively report the clinical management of 3,737 screened patients, including 3,119 (83.5%) treated with HCQ-AZ (200 mg of oral HCQ, three times daily for ten days and 500 mg of oral AZ on day 1 followed by 250 mg daily for the next four days, respectively) for at least three days and 618 (16.5%) patients treated with other regimen (“others”). Outcomes were death, transfer to the intensive care unit (ICU), ≥10 days of hospitalization and viral shedding.
Results
The patients’ mean age was 45 (sd 17) years, 45% were male, and the case fatality rate was 0.9%. We performed 2,065 low-dose computed tomography (CT) scans highlighting lung …
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