作者
Robert A Edwards, Alejandro A Vega, Holly M Norman, Maria Ohaeri, Kyle Levi, Elizabeth A Dinsdale, Ondrej Cinek, Ramy K Aziz, Katelyn McNair, Jeremy J Barr, Kyle Bibby, Stan JJ Brouns, Adrian Cazares, Patrick A de Jonge, Christelle Desnues, Samuel L Diaz Munoz, Peter C Fineran, Alexander Kurilshikov, Rob Lavigne, Karla Mazankova, David T McCarthy, Franklin L Nobrega, Alejandro Reyes Munoz, German Tapia, Nicole Trefault, Alexander V Tyakht, Pablo Vinuesa, Jeroen Wagemans, Alexandra Zhernakova, Frank M Aarestrup, Gunduz Ahmadov, Abeer Alassaf, Josefa Anton, Abigail Asangba, Emma K Billings, Vito Adrian Cantu, Jane M Carlton, Daniel Cazares, Gyu-Sung Cho, Tess Condeff, Pilar Cortés, Mike Cranfield, Daniel A Cuevas, Rodrigo De la Iglesia, Przemyslaw Decewicz, Michael P Doane, Nathaniel J Dominy, Lukasz Dziewit, Bashir Mukhtar Elwasila, A Murat Eren, Charles Franz, Jingyuan Fu, Cristina Garcia-Aljaro, Elodie Ghedin, Kristen M Gulino, John M Haggerty, Steven R Head, Rene S Hendriksen, Colin Hill, Heikki Hyöty, Elena N Ilina, Mitchell T Irwin, Thomas C Jeffries, Juan Jofre, Randall E Junge, Scott T Kelley, Mohammadali Khan Mirzaei, Martin Kowalewski, Deepak Kumaresan, Steven R Leigh, David Lipson, Eugenia S Lisitsyna, Montserrat Llagostera, Julia M Maritz, Linsey C Marr, Angela McCann, Shahar Molshanski-Mor, Silvia Monteiro, Benjamin Moreira-Grez, Megan Morris, Lawrence Mugisha, Maite Muniesa, Horst Neve, Nam-phuong Nguyen, Olivia D Nigro, Anders S Nilsson, Taylor O’connell, Rasha Odeh, Andrew Oliver, Mariana Piuri, Aaron J Prussin Ii, Udi Qimron, Zhe-Xue Quan, Petra Rainetova, Adán Ramírez-Rojas, Raul Raya, Kim Reasor, Gillian AO Rice, Alessandro Rossi, Ricardo Santos, John Shimashita, Elyse N Stachler, Lars C Stene, Ronan Strain, Rebecca Stumpf, Pedro J Torres, Alan Twaddle, MaryAnn Ugochi Ibekwe, Nicolás Villagra, Stephen Wandro, Bryan White, Andy Whiteley, Katrine L Whiteson, Cisca Wijmenga, Maria M Zambrano, Henrike Zschach, Bas E Dutilh
发表日期
2019/10
期刊
Nature microbiology
卷号
4
期号
10
页码范围
1727-1736
出版商
Nature Publishing Group UK
简介
Microbiomes are vast communities of microorganisms and viruses that populate all natural ecosystems. Viruses have been considered to be the most variable component of microbiomes, as supported by virome surveys and examples of high genomic mosaicism. However, recent evidence suggests that the human gut virome is remarkably stable compared with that of other environments. Here, we investigate the origin, evolution and epidemiology of crAssphage, a widespread human gut virus. Through a global collaboration, we obtained DNA sequences of crAssphage from more than one-third of the world’s countries and showed that the phylogeography of crAssphage is locally clustered within countries, cities and individuals. We also found fully colinear crAssphage-like genomes in both Old-World and New-World primates, suggesting that the association of crAssphage with primates may be millions of years old …
引用总数
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