作者
Vincenzo Bagnardi, M Rota, E Botteri, I Tramacere, F Islami, V Fedirko, L Scotti, M Jenab, F Turati, E Pasquali, C Pelucchi, R Bellocco, E Negri, G Corrao, J Rehm, P Boffetta, C La Vecchia
发表日期
2013/2/1
来源
Annals of oncology
卷号
24
期号
2
页码范围
301-308
出版商
Elsevier
简介
Background
There is convincing evidence that alcohol consumption increases the risk of cancer of the colorectum, breast, larynx, liver, esophagus, oral cavity and pharynx. Most of the data derive from studies that focused on the effect of moderate/high alcohol intakes, while little is known about light alcohol drinking (up to 1 drink/day).
Patients and methods
We evaluated the association between light drinking and cancer of the colorectum, breast, larynx, liver, esophagus, oral cavity and pharynx, through a meta-analytic approach. We searched epidemiological studies using PubMed, ISI Web of Science and EMBASE, published before December 2010.
Results
We included 222 articles comprising ∼92 000 light drinkers and 60 000 non-drinkers with cancer. Light drinking was associated with the risk of oropharyngeal cancer [relative risk, RR = 1.17; 95% confidence interval (CI) 1.06–1.29], esophageal squamous cell …
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V Bagnardi, M Rota, E Botteri, I Tramacere, F Islami… - Annals of oncology, 2013