作者
Farhad Islami, Irene Tramacere, Matteo Rota, Vincenzo Bagnardi, Veronika Fedirko, Lorenza Scotti, Werner Garavello, Mazda Jenab, Giovanni Corrao, Kurt Straif, Eva Negri, Paolo Boffetta, Carlo La Vecchia
发表日期
2010/11/1
来源
Oral oncology
卷号
46
期号
11
页码范围
802-810
出版商
Pergamon
简介
Alcohol drinking is a known risk factor for laryngeal cancer. However, little information is available on the risk associated with light alcohol drinking. To address this issue, we conducted a meta-analysis using two methods: (i) random-effects models with reconstruction of alcohol consumption categories and calculation of risk estimates associated with predefined consumption levels using Hamling method and (ii) random-effects meta-regression models. The PubMed database was searched for all case–control or cohort studies published in the English language on the association between alcohol consumption and risk of laryngeal cancer. Forty studies (38 case–control, 2 cohort) reporting on at least three levels of consumption were included. Overall, alcohol drinking versus non-drinking was associated with an approximately 2-fold increase in risk of laryngeal cancer (RR=1.90; 95% CI: 1.59–2.28). While light alcohol …
引用总数
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