作者
George Ostapowicz, Robert J Fontana, Frank V Schiødt, Anne Larson, Timothy J Davern, Steven HB Han, Timothy M McCashland, A Obaid Shakil, J Eileen Hay, Linda Hynan, Jeffrey S Crippin, Andres T Blei, Grace Samuel, Joan Reisch, William M Lee, US Acute Liver Failure Study Group*
发表日期
2002/12/17
期刊
Annals of internal medicine
卷号
137
期号
12
页码范围
947-954
出版商
American College of Physicians
简介
Background
Because acute liver failure is rare, related data have been sparse. Studies have suggested that viral hepatitis is the most common underlying cause of this condition.
Objective
To describe the clinical features, presumed causes, and short-term outcomes of acute liver failure.
Design
Prospective cohort study.
Setting
17 tertiary care centers participating in the U.S. Acute Liver Failure Study Group.
Patients
308 consecutive patients with acute liver failure, admitted over a 41-month period.
Measurements
Detailed clinical and laboratory data collected during hospitalization, including outcome 3 weeks after study admission.
Results
73% of patients were women; median age was 38 years. Acetaminophen …
引用总数
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