作者
Ahmad Jayedi, Sakineh Shab-Bidar
发表日期
2018/1/1
来源
Obesity research & clinical practice
卷号
12
期号
1
页码范围
16-28
出版商
Elsevier
简介
Objective
The present study examined the dose–response association of body mass index (BMI) and risk of all-cause and cardiovascular mortality in patients with existing hypertension.
Method
A systematic search was done using PubMed and Scopus, from their inception up to January 25, 2017. Prospective and retrospective cohort studies reporting risk estimates of all-cause and cardiovascular mortality for three or more quantitative categories of BMI were included. Studies which reported results as continuous also were included. Pooled relative risks (RRs) were calculated using random effects models.
Results
Of initial 34,938 identified studies, 14 studies with a total of 489,222 hypertensive patients, involving 41,872 cases of all-cause mortality and 2,123 cases of cardiovascular mortality were included. A five-unit increment in BMI was associated with an 8% reduction in the risk of all-cause mortality (Pooled RR: 0 …
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A Jayedi, S Shab-Bidar - Obesity research & clinical practice, 2018