作者
Samuel Der Sarkissian, Schapoor Hessam, Joslyn S Kirby, Michelle A Lowes, Dillon Mintoff, Haley B Naik, Hans Christian Ring, Nisha Suyien Chandran, John W Frew
发表日期
2022/3/1
来源
JAMA dermatology
卷号
158
期号
3
页码范围
300-313
出版商
American Medical Association
简介
Importance
The identification and validation of biomarkers in hidradenitis suppurativa (HS) has potential to improve the understanding and management of this chronic, burdensome disease.
Objective
To systematically identify all known HS biomarkers, categorize them by biomarker type, and critically evaluate their validity according to established criteria.
Evidence Review
Eligibility criteria for this review (PROSPERO Registration 230830) included randomized clinical trials, uncontrolled clinical trials, cohort studies, case-control studies, and other observational studies with no restrictions of patient age, sex, race or ethnicity, or language of publication up until December 31, 2020. All articles were categorized into biomarker type, defined using the US Food and Drug Administration Biomarkers, Endpoints, and other Tools (BEST) glossary. Assessment of each identified biomarker was undertaken in line with the US Food …
引用总数