作者
Santosh B Murthy, Sung-Min Cho, Ajay Gupta, Ashkan Shoamanesh, Babak B Navi, Radhika Avadhani, Joshua Gruber, Yunke Li, Tatiana Greige, Vasileios-Arsenios Lioutas, Casey Norton, Cenai Zhang, Pitchaiah Mandava, Costantino Iadecola, Guido J Falcone, Kevin N Sheth, Alessandro Biffi, Jonathan Rosand, Adnan I Qureshi, Joshua N Goldstein, Chelsea Kidwell, Issam Awad, Magdy Selim, Daniel F Hanley, Daniel Woo, Hooman Kamel, Wendy C Ziai
发表日期
2020/11/1
期刊
JAMA neurology
卷号
77
期号
11
页码范围
1390-1397
出版商
American Medical Association
简介
Importance
The etiology and significance of diffusion-weighted imaging (DWI) lesions in patients with acute intracerebral hemorrhage (ICH) remain unclear.
Objective
To evaluate which factors are associated with DWI lesions, whether associated factors differ by ICH location, and whether DWI lesions are associated with functional outcomes.
Design, Setting, and Participants
This analysis pooled individual patient data from 3 randomized clinical trials (Minimally Invasive Surgery Plus Alteplase for Intracerebral Hemorrhage Evacuation phase 3 trial, Antihypertensive Treatment of Acute Cerebral Hemorrhage trial, and Intracerebral Hemorrhage Deferoxamine phase 2 trial) and 1 multicenter prospective study (Ethnic/Racial Variations of Intracerebral Hemorrhage). Patients were enrolled from August 1, 2010, to September 30, 2018. Of the 4782 patients, 1788 who underwent magnetic resonance imaging scans of the brain …
学术搜索中的文章
SB Murthy, SM Cho, A Gupta, A Shoamanesh, BB Navi… - JAMA neurology, 2020