作者
E Bernabé, EK Delgado-Angulo, JE Murasko, W Marcenes, N Wellappuli, N Amarasena, F Frasseto, TM Parisotto, RCR Peres, MR Marques, SRP Line, M Nobre dos Santos, M Laitala, P Alanen, P Isokangas, E Söderling, K Pienihäkkinen, K Lester, RS Simmonds, M Toledano, M Yamauti, E Osorio, R Osorio, KA Plonka, ML Pukallus, AG Barnett, LJ Walsh, TH Holcombe, WK Seow, AB Nongonierma, RJ FitzGerald, X Wang, MC Willing, ML Marazita, S Wendell, JJ Warren, B Broffitt, B Smith, T Busch, AC Lidral, SM Levy, Satz Mengensatzproduktion, Druck Reinhardt Druck Basel
发表日期
2012
期刊
Caries Research
卷号
46
期号
3
页码范围
268-338
出版商
Karger Publishers
简介
This study aimed to assess the surface roughness and width of enamel matrix apatite crystals of mice susceptible (A/J strain) or resistant (129 P3/J strain) to dental fluorosis through analyses by AFM (atomic force microscopy). Samples from the enamel matrix in the early stages of secretion and maturation were obtained from the incisors of both mice strains after sacrifice. All detectable traces of matrix protein were removed from the samples by a sequential extraction procedure. The protein-free crystals (n= 13 per strain) were analysed qualitatively in the AFM. Crystal surface roughness (Ra) and width were measured. The mean (8 SD) Ra of the crystals of A/J strain (0.58 8 0.15 nm) was lower than the one found for the 129P3/J strain (0.66 8 0.21 nm) but the difference did not reach statistical significance (t= 1.187, p= 0.247). Crystal width of the 129P3/J strain (70.42 8 6.79 nm) was found to be significantly smaller (t …
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E Bernabé, EK Delgado-Angulo, JE Murasko… - Caries Research, 2012