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Introduction Injury is a leading cause for morbidity and mortality in otherwise healthy children. There are few data (especially in Iran)about epidemiology and incidence of injury in the first two years of life. Materials and Methods This research was a cross sectional descriptive study on a group of 1000 infants (6-24 months old), from all the health care centers in Mashhad, who were evaluated about the history of any kind of injury since birth. The study was performed in autumn of 2004. Results The mean age of the study group was 13.8±7.8 months. During this time 55.7% of the infants had experienced some kind of injury.The occurred injuries in order of frequency were Falls (13.4%), Chocking due to foreign body aspiration (12.8%), Cuts and lacerations (11.9%), Burning (10.9%), Poisoning (3.9%) Traffic accidents (1.5%) Drowning (0.7%) and electrical injuries (0.6%). Overall Fifty infants (5%) in our group were visited …