作者
Xiao Liu, Ziqi Tan, Yuna Huang, Huilei Zhao, Menglu Liu, Peng Yu, Jianyong Ma, Yujie Zhao, Wengen Zhu, Jingfeng Wang
发表日期
2022/7/1
来源
Cardiovascular Diabetology
卷号
21
期号
1
页码范围
124
出版商
BioMed Central
简介
Background
The triglyceride-glucose (TyG) index is a new alternative measure for insulin resistance. This meta-analysis was conducted to assess the associations of the TyG index with the risks of cardiovascular diseases and mortality in the general population.
Methods
The PubMed, Cochrane Library and Embase databases were searched for randomized controlled trials or observational cohort studies reporting associations of the TyG index with cardiovascular diseases and mortality from inception to April 16, 2022. Effect sizes were pooled using random-effects models. Robust error meta-regression methods were applied to fit nonlinear dose–response associations. Evidence quality levels and recommendations were assessed using the Grading of Recommendations Assessment, Development and Evaluation system (GRADE).
Results
Twelve cohort studies (6 prospective and 6 retrospective cohorts) involving 6 …
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X Liu, Z Tan, Y Huang, H Zhao, M Liu, P Yu, J Ma… - Cardiovascular Diabetology, 2022
