作者
Yehuda Shoenfeld, Roberto Gerli, Andrea Doria, Eiji Matsuura, Marco Matucci Cerinic, Nicoletta Ronda, Luis J Jara, Mahmud Abu-Shakra, Pier Luigi Meroni, Yaniv Sherer
发表日期
2005/11/22
来源
Circulation
卷号
112
期号
21
页码范围
3337-3347
出版商
Lippincott Williams & Wilkins
简介
antibodies concomitant with larger atherosclerotic lesions that contained abundant CD4 cells. OxLDL is the type of LDL that is more likely to undergo uptake by macrophages, which turn into the foam cells characterizing atherosclerotic lesions. Anti-oxLDL antibodies are present in patients with atherosclerosis, those with AIRDs, and healthy individuals. 8 In multivariate analyses, anti-oxLDL autoantibodies discriminated better between patients with peripheral vascular disease and control subjects than did any of the different lipoprotein analyses. There was also a tendency for higher autoantibody levels in patients with more extensive atherosclerosis. 9 The autoantibodies to ox-LDL were investigated in several AIRD groups, including patients with systemic sclerosis (SSc), 10 systemic vasculitides, 8 and systemic lupus erythematosus (SLE). 10 The antibody levels were higher in those patient groups than in control …
引用总数
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学术搜索中的文章
Y Shoenfeld, R Gerli, A Doria, E Matsuura, MM Cerinic… - Circulation, 2005