作者
Bronner P Gonçalves, Simon R Procter, Proma Paul, Jaya Chandna, Alexandra Lewin, Farah Seedat, Artemis Koukounari, Ziyaad Dangor, Shannon Leahy, Sridhar Santhanam, Hima B John, Justina Bramugy, Azucena Bardají, Amina Abubakar, Carophine Nasambu, Romina Libster, Clara Sánchez Yanotti, Erzsébet Horváth-Puhó, Henrik T Sørensen, Diederik van de Beek, Merijn W Bijlsma, William M Gardner, Nicholas Kassebaum, Caroline Trotter, Quique Bassat, Shabir A Madhi, Philipp Lambach, Mark Jit, Joy E Lawn, Kirstine K Søgaard, Merel N van Kassel, Linde Snoek, Brechje de Gier, Arie van der Ende, Susan JM Hahné, Lois M Harden, Azra Ghoor, Sibongile Mbatha, Sarah Lowick, Barbara Laughton, Tamara Jaye, Sanjay G Lala, Pamela Sithole, Jacqueline Msayi, Ntombifuthi Kumalo, Tshepiso Nompumelelo Msibi, Asha Arumugam, Nandhini Murugesan, Nandhini Rajendraprasad, Mohana Priya, Adam Mabrouk, Patrick Vidzo Katana, Eva Mwangome, Charles R Newton, Humberto Mucasse, Celine Aerts, Sergio Massora, Valeria Medina, Andrea Rojas, Daniel Amado, Conrado J Llapur, AKM Tanvir Hossain, Qazi Sadeq-ur Rahman, Margaret Ip, Anna Seale, Paul T Heath, Kirsty Le Doare, Asma Khalil, Stephanie J Schrag, Ajoke Sobanjo-ter Meulen, Elizabeth Mason, Dianna M Blau, Shams El Arifeen, Nega Assefa, Dickens Onyango, Samba O Sow, Inacio Mandomando, Ikechukwu Ogbuanu, Karen L Kotloff, J Anthony G Scott, Emily S Gurley, Beth A Tippet Barr, Sana Mahtab
发表日期
2022/6/1
期刊
The Lancet Global Health
卷号
10
期号
6
页码范围
e807-e819
出版商
Elsevier
简介
Background
Group B streptococcus (GBS) colonisation during pregnancy can lead to invasive GBS disease (iGBS) in infants, including meningitis or sepsis, with a high mortality risk. Other outcomes include stillbirths, maternal infections, and prematurity. There are data gaps, notably regarding neurodevelopmental impairment (NDI), especially after iGBS sepsis, which have limited previous global estimates. In this study, we aimed to address this gap using newly available multicountry datasets.
Methods
We collated and meta-analysed summary data, primarily identified in a series of systematic reviews published in 2017 but also from recent studies on NDI and stillbirths, using Bayesian hierarchical models, and estimated the burden for 183 countries in 2020 regarding: maternal GBS colonisation, iGBS cases and deaths in infants younger than 3 months, children surviving iGBS affected by NDI, and maternal iGBS …
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BP Gonçalves, SR Procter, P Paul, J Chandna, A Lewin… - The Lancet Global Health, 2022