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The author expresses his ever indebtedness, deepest sense of gratitude, sincere appreciation and profound regards to his reverend and beloved teacher and Research Supervisor Professor Dr. Md. Shahidur Rahman Khan, Department of Microbiology and Hygiene, Bangladesh Agricultural University (BAU), Mymensingh, for his scholastic guidance, uncompromising principles, sympathetic supervision, valuable advice, constant inspiration, affectionate feeling, radical investigation and constructive criticism in all phases of this study and preparing the manuscript.

The author is ever grateful, immensely indebted to his honorable and respected research co-supervisor, Dr. Munirul Alam, Scientist, Enteric Microbiology Laboratory, Laboratory Science Division, International Center for Diarrhoeal Disease Research in Bangladesh (icddr, b), Dhaka, for his sincere co-operation, valuable work plan, suggestions, supervision and advise for completion of this research work.