作者
F Guerreiro, Ninon Burgos, A Dunlop, K Wong, I Petkar, C Nutting, K Harrington, S Bhide, K Newbold, D Dearnaley, NM Desouza, VA Morgan, J McClelland, S Nill, MJ Cardoso, S Ourselin, U Oelfke, AC Knopf
发表日期
2017/3/1
期刊
Physica Medica
卷号
35
页码范围
7-17
出版商
Elsevier
简介
Background and purpose
Computed tomography (CT) imaging is the current gold standard for radiotherapy treatment planning (RTP). The establishment of a magnetic resonance imaging (MRI) only RTP workflow requires the generation of a synthetic CT (sCT) for dose calculation. This study evaluates the feasibility of using a multi-atlas sCT synthesis approach (sCTa) for head and neck and prostate patients.
Material and methods
The multi-atlas method was based on pairs of non-rigidly aligned MR and CT images. The sCTa was obtained by registering the MRI atlases to the patient’s MRI and by fusing the mapped atlases according to morphological similarity to the patient. For comparison, a bulk density assignment approach (sCTbda) was also evaluated. The sCTbda was obtained by assigning density values to MRI tissue classes (air, bone and soft-tissue). After evaluating the synthesis accuracy of the sCTs …
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F Guerreiro, N Burgos, A Dunlop, K Wong, I Petkar… - Physica Medica, 2017