作者
Bryan Chong, Gwyneth Kong, Kannan Shankar, HS Jocelyn Chew, Chaoxing Lin, Rachel Goh, Yip Han Chin, Darren Jun Hao Tan, Kai En Chan, Wen Hui Lim, Nicholas Syn, Siew Pang Chan, Jiong-Wei Wang, Chin Meng Khoo, Georgios K Dimitriadis, Karn Wijarnpreecha, Arun Sanyal, Mazen Noureddin, Mohammad Shadab Siddiqui, Roger Foo, Anurag Mehta, Gemma A Figtree, Derek J Hausenloy, Mark Y Chan, Cheng Han Ng, Mark Muthiah, Mamas A Mamas, Nicholas WS Chew
发表日期
2023/4/1
期刊
Metabolism
卷号
141
页码范围
155402
出版商
WB Saunders
简介
Background
A significant proportion of premature deaths globally are related to metabolic diseases in young adults. We examined the global trends and mortality of metabolic diseases in individuals aged below 40 years using data from the Global Burden of Diseases, Injuries and Risk Factors Study (GBD) 2019.
Methods
From 2000 to 2019, global estimates of deaths and disability-adjusted life years (DALYs) were described for metabolic diseases (type 2 diabetes mellitus [T2DM], hyperlipidemia, hypertension, obesity, non-alcoholic fatty liver disease [NAFLD]). Subgroup analyses were performed based on sex, geographical regions and Socio-Demographic Index (SDI). Age-standardised death and DALYs were presented per 100,000 population with 95 % uncertainty intervals (UI). Projections of mortality and DALYs were estimated using regression models based on the GBD 2019 data and combining them with …
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B Chong, G Kong, K Shankar, HSJ Chew, C Lin, R Goh… - Metabolism, 2023