作者
GV Ramesh Prasad, Andrew T Yan, Michelle M Nash, S Joseph Kim, Ron Wald, Rachel Wald, Charmaine Lok, Lakshman Gunaratnam, Gauri R Karur, Anish Kirpalani, Philip W Connelly
发表日期
2018/11
期刊
Canadian Journal of Kidney Health and Disease
卷号
5
页码范围
2054358118809974
出版商
SAGE Publications
简介
Background
Cardiac magnetic resonance (CMR) imaging accurately and precisely measures left ventricular (LV) mass and function. Identifying mechanisms by which LV mass change and functional improvement occur in some end-stage kidney disease (ESKD) patients may help to appropriately target kidney transplant (KT) recipients for further investigation and intervention. The concentration of serum adiponectin, a cardiovascular biomarker, increases in cardiac failure, its production being enhanced by B-type natriuretic peptide (BNP), and both serum adiponectin and BNP concentrations decline posttransplantation.
Objective
We tested the hypothesis that kidney transplantation alters LV characteristics that relate to serum adiponectin concentrations.
Design
Prospective and observational cohort study.
Setting
The study was performed at 3 adult kidney transplant and dialysis centers in Ontario, Canada.
Patients
A total …
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GVR Prasad, AT Yan, MM Nash, SJ Kim, R Wald… - Canadian Journal of Kidney Health and Disease, 2018