作者
Marco De Simone, Michele Chirichella, Stefan Emming, Saveria Mazzara, Valeria Ranzani, Paola Gruarin, Giorgia Moschetti, Nadia Pulvirenti, Stefano Maglie, Chiara Vasco, Maria Cristina Crosti, Grazisa Rossetti, Massimiliano Pagani, Sergio Abrignani, Silvia Monticelli, Jens Geginat
发表日期
2021/12
期刊
European Journal of Immunology
卷号
51
期号
12
页码范围
3243
出版商
Wiley
简介
Ex vivo gene expression and miRNA profiling of Eomes+ Tr1‐like cells suggested that they represent a differentiation stage that is intermediate between Th1‐cells and cytotoxic CD4+ T‐cells. Several microRNAs were downregulated in Eomes+ Tr1‐like cells that might inhibit Tr1‐cell differentiation. In particular, miR‐92a targeted Eomes, while miR‐125a inhibited IFN‐g and IL‐10R expression.
学术搜索中的文章
M De Simone, M Chirichella, S Emming, S Mazzara… - European Journal of Immunology, 2021