作者
Lorenzo Maggi, Marco Moscatelli, Rita Frangiamore, Federica Mazzi, Mattia Verri, Alberto De Luca, Maria Barbara Pasanisi, Giovanni Baranello, Irene Tramacere, Luisa Chiapparini, Maria Grazia Bruzzone, Renato Mantegazza, Domenico Aquino
发表日期
2021/3
期刊
Clinical neuroradiology
卷号
31
页码范围
257-266
出版商
Springer Berlin Heidelberg
简介
Purpose
Aim of this study is to compare Quantitative Magnetic Resonance Imaging (qMRI) measures between Becker Muscular Dystrophy (BMD) and Healthy Subjects (HS) and to correlate these parameters with clinical scores.
Methods
Ten BMD patients (mean age ±standard deviation: 38.7 ± 15.0 years) and ten age-matched HS, were investigated through magnetic resonance imaging (MRI) at thigh and calf levels, including: 1) a standard axial T1-weighted sequence; 2) a volumetric T2-weighted sequence; 3) a multiecho spin-echo sequence; 4) a 2-point Dixon sequence; 5) a Diffusion Tensor Imaging (DTI) sequence.
Results
Mean Fat Fraction (FF), T2-relaxation time and Fractional Anisotropy (FA) DTI at thigh and calf levels were significantly higher in BMD patients than in HS (p-values < 0.01). FF at thigh and calf …
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L Maggi, M Moscatelli, R Frangiamore, F Mazzi, M Verri… - Clinical neuroradiology, 2021