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The intensity of the use of antidepressants in large populations can nowadays relatively easily be estimated using databases encompassing prescription data. There are shortcomings when using prescription databases as they contain no clinical data on patient illness. Antidepressants are prescribed for different illnesses, thus information on the indications could help when interpreting results from database studies on antidepressant drug use. The aim of this study is to investigate for which indications antidepressants are being prescribed in general practice in the Netherlands.

Data were obtained from the Second Dutch National Survey of General Practice, carried out by NIVEL (N=385,461). Patients, 18 years and older, who received an antidepressant prescription from a general practitioner in 2001 were selected (N=13,835). Indications for antidepressant drug prescribing were …