作者
Victoria Abbing-Karahagopian, Consuelo Huerta, PC Souverein, F De Abajo, HGM Leufkens, J Slattery, Y Alvarez, M Miret, M Gil, B Oliva, U Hesse, G Requena, F De Vries, M Rottenkolber, S Schmiedl, R Reynolds, RG Schlienger, MCH De Groot, OH Klungel, TP Van Staa, L Van Dijk, ACG Egberts, H Gardarsdottir, ML De Bruin
发表日期
2014/7
期刊
European journal of clinical pharmacology
卷号
70
页码范围
849-857
出版商
Springer Berlin Heidelberg
简介
Purpose
Drug utilization studies have applied different methods to various data types to describe medication use, which hampers comparisons across populations. The aim of this study was to describe the time trends in antidepressant prescribing in the last decade and the variation in the prevalence, calculated in a uniform manner, in seven European electronic healthcare databases.
Methods
Annual prevalence per 10,000 person-years (PYs) was calculated for 2001–2009 in databases from Spain, Germany, Denmark, the United Kingdom (UK), and the Netherlands. Prevalence data were stratified according to age, sex, antidepressant type (selective serotonin re-uptake inhibitors [SSRIs] or tricyclic antidepressants [TCAs]) and major indications.
Results
The age- and sex-standardized prevalence was lowest in the two …
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V Abbing-Karahagopian, C Huerta, PC Souverein… - European journal of clinical pharmacology, 2014