作者
Prasanth Balasubramanian, Shahin Isha, Abby J Hanson, Anna Jenkins, Parthkumar Satashia, Arvind Balavenkataraman, Iván A Huespe, Vikas Bansal, Sean M Caples, Syed Anjum Khan, Nitesh K Jain, Rahul Kashyap, Rodrigo Cartin-Ceba, Joseph L Nates, Dereddi RS Reddy, Ricardo Diaz Milian, Houssam Farres, Archer K Martin, Parag C Patel, Michael A Smith, Anna B Shapiro, Anirban Bhattacharyya, Sanjay Chaudhary, Sean P Kiley, Quintin J Quinones, Neal M Patel, Pramod K Guru, Pablo Moreno Franco, Devang K Sanghavi
发表日期
2023/12/1
期刊
Journal of critical care
卷号
78
页码范围
154378
出版商
WB Saunders
简介
Purpose
To evaluate the association of estimated plasma volume (ePV) and plasma volume status (PVS) on admission with the outcomes in COVID-19-related acute respiratory distress syndrome (ARDS) patients.
Materials and methods
We performed a retrospective multi-center study on COVID-19-related ARDS patients who were admitted to the Mayo Clinic Enterprise health system. Plasma volume was calculated using the formulae for ePV and PVS, and these variables were analyzed for correlation with patient outcomes.
Results
Our analysis included 1298 patients with sequential organ failure assessment (SOFA) respiratory score ≥ 2 (PaO2/FIO2 ≤300 mmHg) and a mortality rate of 25.96%. A Cox proportional multivariate analysis showed PVS but not ePV as an independent correlation with 90-day mortality after adjusting for the covariates (HR: 1.015, 95% CI: 1.005–1.025, p = 0.002 and HR 1.054, 95% CI 0 …
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P Balasubramanian, S Isha, AJ Hanson, A Jenkins… - Journal of critical care, 2023