作者
Sjors Verlaan, Andrea B Maier, Jürgen M Bauer, Ivan Bautmans, Kirsten Brandt, Lorenzo M Donini, Marcello Maggio, Marion ET McMurdo, Tony Mets, Chris Seal, Sander LJ Wijers, Cornel Sieber, Yves Boirie, Tommy Cederholm
发表日期
2018/4/1
期刊
Clinical Nutrition
卷号
37
期号
2
页码范围
551-557
出版商
Churchill Livingstone
简介
Background
Inadequate nutritional intake and altered response of aging muscles to anabolic stimuli from nutrients contribute to the development of sarcopenia. Nutritional interventions show inconsistent results in sarcopenic older adults, which might be influenced by their basal nutritional status.
Objective
To test if baseline serum 25-hydroxyvitamin D (25(OH)D) concentrations and dietary protein intake influenced changes in muscle mass and function in older adults who received nutritional intervention.
Methods and design
Post-hoc analysis was performed in the PROVIDE study that was a randomized controlled, double blind trial among 380 sarcopenic older adults. This study showed that those who received a vitamin D and leucine-enriched whey protein medical nutrition drink for 13 weeks gained more appendicular muscle mass (aMM), and improved lower-extremity function as assessed by the chair stand test …
学术搜索中的文章
S Verlaan, AB Maier, JM Bauer, I Bautmans, K Brandt… - Clinical Nutrition, 2018