作者
Sima Rugarabamu, Leonard Mboera, Mark Rweyemamu, Gaspary Mwanyika, Julius Lutwama, Janusz Paweska, Gerald Misinzo
发表日期
2020/3/1
来源
BMJ Global Health
卷号
5
期号
3
页码范围
e001955
出版商
BMJ Specialist Journals
简介
Introduction
Ebola virus disease (EVD) is one of the deadliest haemorrhagic fevers affecting humans and non-human primates. Thirty-four outbreaks have been reported in Africa since it was first recognised in 1976. This review analysed 42 years of EVD outbreaks and identified various challenges and opportunities for its control and prevention in Sub-Saharan Africa.
Methods
A literature search of relevant articles on EVD was done in PubMed, Web of Science and Google Scholar electronic databases. Articles published from 1976 to 2019 were reviewed to document reports of EVD outbreaks in Sub-Saharan Africa. Data extraction focused on the year of outbreak, geographical spread, virus strain involved, number of cases and deaths, case fatality, and outbreak management. Analyses of trends in case fatality were performed by calculating ORs between times.
Results
In the past four decades, a total of 34 EVD …
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