作者
Iftihar Koksal, Gurdal Yilmaz, Firdevs Aksoy, Hava Aydin, Ilknur Yavuz, Serap Iskender, Korhan Akcay, Sukru Erensoy, Rahmet Caylan, Kemalettin Aydin
发表日期
2010/1/1
期刊
Journal of Clinical Virology
卷号
47
期号
1
页码范围
65-68
出版商
Elsevier
简介
BACKGROUND
The efficiency of ribavirin for treatment of Crimean-Congo hemorrhagic fever (CCHF) is unknown. In the literature, prospective randomized studies investigating the efficacy of ribavirin are not found.
OBJECTIVES
To investigate the efficacy of ribavirin in treatment of patients with CCHF.
STUDY DESIGN
In this prospective randomized cohort study 136 cases were included between June 2004 and August 2007. The diagnosis was confirmed in the CCHF reference laboratory of Refik Saydam National Hygiene Central Institute of the Turkish Ministry of Health. Patients either received ribavirin plus supportive treatment (Group A) (n=64) or only supportive treatment (Group B) (n=72). For the evaluation of efficacy of ribavirin, various parameters were compared between Group A and Group B.
RESULTS
As well as the similarity of demographic features between the two groups, there were no statistical …
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I Koksal, G Yilmaz, F Aksoy, H Aydin, I Yavuz… - Journal of Clinical Virology, 2010