作者
Donn J Colby, Lydie Trautmann, Suteeraporn Pinyakorn, Louise Leyre, Amelie Pagliuzza, Eugene Kroon, Morgane Rolland, Hiroshi Takata, Supranee Buranapraditkun, Jintana Intasan, Nitiya Chomchey, Roshell Muir, Elias K Haddad, Sodsai Tovanabutra, Sasiwimol Ubolyam, Diane L Bolton, Brandie A Fullmer, Robert J Gorelick, Lawrence Fox, Trevor A Crowell, Rapee Trichavaroj, Robert O’Connell, Nicolas Chomont, Jerome H Kim, Nelson L Michael, Merlin L Robb, Nittaya Phanuphak, Jintanat Ananworanich
发表日期
2018/7
期刊
Nature medicine
卷号
24
期号
7
页码范围
923-926
出版商
Nature Publishing Group US
简介
Antiretroviral therapy during the earliest stage of acute HIV infection (Fiebig I) might minimize establishment of a latent HIV reservoir and thereby facilitate viremic control after analytical treatment interruption. We show that 8 participants, who initiated treatment during Fiebig I and were treated for a median of 2.8 years, all experienced rapid viral load rebound following analytical treatment interruption, indicating that additional strategies are required to control or eradicate HIV.
学术搜索中的文章
DJ Colby, L Trautmann, S Pinyakorn, L Leyre… - Nature medicine, 2018