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Objective

Available evidence about risk factors for preeclampsia is limited by the study design, data source, lack of appropriate adjustment and outdated data. A better knowledge of the main subgroups at risk could help define preventive strategies. The study objective was to determine the strength and attributable fraction of clinical risk factors for preeclampsia.

Study Design

Data from the French national perinatal surveys, repeated cross-sectional surveys including all women delivering during one week in all maternity units in France in 2016 (n= 13896) and 2021 (n= 13404) was used. After exclusion of women without data on the occurrence of hypertensive disorders of pregnancy (HDP), 25941 women were included. Multivariable Poisson regression models with adjusted relative risks (aRR) were used to identify risk factors in two steps: 1/present at antenatal care booking, 2/those emerging as pregnancy …