作者
Edouard Leyne, Olivia Anselem, Pénélope Jordan, Alexandre J Vivanti, Alexandra Benachi, Laurent Salomon, Mathilde Jacquier, Jean‐Marie Jouannic, Ferdinand Dhombres, Tatiana Cambier, Jonathan Rosenblatt, Emmanuelle Pannier, François Goffinet, Vassilis Tsatsaris, Yoann Athiel
发表日期
2024/1
期刊
Acta Obstetricia et Gynecologica Scandinavica
卷号
103
期号
1
页码范围
51-58
简介
Introduction
The aim of this study is to evaluate the benefit of cytogenetic testing by amniocentesis after an ultrasound diagnosis of isolated bilateral talipes equinovarus.
Material and methods
This multicenter observational retrospective study includes all prenatally diagnosed cases of isolated bilateral talipes equinovarus in five fetal medicine centers from 2012 through 2021. Ultrasound data, amniocentesis results, biochemical analyses of amniotic fluid and parental blood samples to test neuromuscular diseases, pregnancy outcomes, and postnatal outcomes were collected for each patient.
Results
In all, 214 fetuses with isolated bilateral talipes equinovarus were analyzed. A first‐degree family history of talipes equinovarus existed in 9.8% (21/214) of our cohort. Amniocentesis was proposed to 86.0% (184/214) and performed in 70.1% (129/184) of cases. Of the 184 karyotypes performed, two (1.6%) were …
学术搜索中的文章
E Leyne, O Anselem, P Jordan, AJ Vivanti, A Benachi… - Acta Obstetricia et Gynecologica Scandinavica, 2024