作者
Katherine L Mills, Maree Teesson, Sudie E Back, Kathleen T Brady, Amanda L Baker, Sally Hopwood, Claudia Sannibale, Emma L Barrett, Sabine Merz, Julia Rosenfeld, Philippa L Ewer
发表日期
2012/8/15
期刊
Jama
卷号
308
期号
7
页码范围
690-699
出版商
American Medical Association
简介
Context
There is concern that exposure therapy, an evidence-based cognitive-behavioral treatment for posttraumatic stress disorder (PTSD), may be inappropriate because of risk of relapse for patients with co-occurring substance dependence.
Objective
To determine whether an integrated treatment for PTSD and substance dependence, Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure (COPE), can achieve greater reductions in PTSD and substance dependence symptom severity compared with usual treatment for substance dependence.
Design, Setting, and Participants
Randomized controlled trial enrolling 103 participants who met DSM-IV-TR criteria for both PTSD and substance dependence. Participants were recruited from 2007-2009 in Sydney, Australia; outcomes were assessed at 9 months postbaseline, with interim measures collected at 6 weeks and 3 months …
学术搜索中的文章
KL Mills, M Teesson, SE Back, KT Brady, AL Baker… - Jama, 2012