作者
Daniel T Corp, Hannah GK Bereznicki, Gillian M Clark, George J Youssef, Peter J Fried, Ali Jannati, Charlotte B Davies, Joyce Gomes-Osman, Julie Stamm, Sung Wook Chung, Steven J Bowe, Nigel C Rogasch, Paul B Fitzgerald, Giacomo Koch, Vincenzo Di Lazzaro, Alvaro Pascual-Leone, Peter G Enticott
发表日期
2020/9/1
期刊
Brain Stimulation
卷号
13
期号
5
页码范围
1476-1488
出版商
Elsevier
简介
Background
Many studies have attempted to identify the sources of interindividual variability in response to theta-burst stimulation (TBS). However, these studies have been limited by small sample sizes, leading to conflicting results.
Objective/Hypothesis
This study brought together over 60 TMS researchers to form the ‘Big TMS Data Collaboration’, and create the largest known sample of individual participant TBS data to date. The goal was to enable a more comprehensive evaluation of factors driving TBS response variability.
Methods
118 corresponding authors of TMS studies were emailed and asked to provide deidentified individual TMS data. Mixed-effects regression investigated a range of individual and study level variables for their contribution to iTBS and cTBS response variability.
Results
430 healthy participants’ TBS data was pooled across 22 studies (mean age = 41.9; range = 17–82; females = 217 …
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DT Corp, HGK Bereznicki, GM Clark, GJ Youssef… - Brain stimulation, 2020