查看文章

Objective To assess the clinical effectiveness of endoscopic laser coagulation of placental vessels in the

Design Prospective study.

Setting Three referral centres for the management of twin‐to‐twin transfusion syndrome.

Population One hundred and thirty‐two pregnancies complicated by severe twin‐to‐twin transfusion syndrome, reflected by polyhydramnios and enlarged bladder of one twin and oligoanhydramnios and collapsed bladder of the other twin, presenting before 28 weeks of gestation.

Methods Prospective collection of data on pre‐procedure assessment, the procedure and the follow up were collected prospectively. Laser coagulation of placental vessels crossing the intertwine membrane on the chorionic surface under sono‐endoscopic guidance, followed by amniodrainage.

Main outcome measures Maternal and pregnancy complications, perinatal death and morbidity were …