作者
Hans‐Peter Frey, Sophie Molholm, Edmund C Lalor, Natalie N Russo, John J Foxe
发表日期
2013/7
期刊
European Journal of Neuroscience
卷号
38
期号
1
页码范围
2125-2138
简介
A key feature of early visual cortical regions is that they contain discretely organized retinotopic maps. Titration of these maps must occur through experience, and the fidelity of their spatial tuning will depend on the consistency and accuracy of the eye movement system. Anomalies in fixation patterns and the ballistics of eye movements are well documented in autism spectrum disorder (ASD), with off‐center fixations a hallmark of the phenotype. We hypothesized that these atypicalities might affect the development of visuo‐spatial maps and specifically that peripheral inputs might receive altered processing in ASD. Using high‐density recordings of visual evoked potentials (VEPs) and a novel system‐identification approach known as VESPA (visual evoked spread spectrum analysis), we assessed sensory responses to centrally and peripherally presented stimuli. Additionally, input luminance was varied to bias …
学术搜索中的文章
HP Frey, S Molholm, EC Lalor, NN Russo, JJ Foxe - European Journal of Neuroscience, 2013