作者
Ivan FN Hung, Angela YM Leung, Daniel WS Chu, Doris Leung, Terence Cheung, Chi-Kuen Chan, Cindy LK Lam, Shao-Haei Liu, Chung-Ming Chu, Pak-Leung Ho, Sophia Chan, Tai-Hing Lam, Raymond Liang, Kwok-Yung Yuen
发表日期
2010/11/1
期刊
Clinical Infectious Diseases
卷号
51
期号
9
页码范围
1007-1016
出版商
The University of Chicago Press
简介
Background . DespiteWorld Health Organization recommendations, the rate of 23-valent pneumococcal (PPV) and influenza (TIV) vaccination among elderly persons in Hong Kong, China, is exceptionally low because of doubts about effectiveness of vaccination. The efficacy of dual vaccination remains unknown.
Methods . From 3 December 2007 to 30 June 2008, we conducted a prospective cohort study by recruiting outpatients aged ⩾65 years with chronic illness to participate in a PPV and TIV vaccination program. All were observed until 31 March 2009. The outcome of subjects, including the rates of death, hospitalization, pneumonia, ischemic stroke, acute myocardial infarction, and coronary and intensive care admissions, were determined.
Results . Of the 36,636 subjects recruited, 7292 received both PPV and TIV, 2076 received TIV …
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