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Methods:

In this retrospective 10-year cohort study, we analyzed all patients who underwent lung transplantation from 2009-2019. Time-to-event analysis using Cox proportional hazards model was utilized for mortality, acute rejection by biopsy, and the development of CLAD, testing pre-and post-transplant motility as a predictor for the above adjusted for age, gender, BMI, and transplant status (single vs. double lung). Manometric diagnosis was done using Chicago Classification 4.0. Pre-transplant GERD was defined based on> 6% time pH< 4, abnormal DeMeester score, evidence of Barrett’s esophagus, peptic strictures, and/or esophagitis.

Results:

227 patients who underwent lung transplantation were analyzed in this study. 79 patients underwent pre-operative manometry (as per guidelines at the time of their pre-transplant evaluation) with the most common diagnosis being normal (87%, n= 66), Ineffective Motility …