作者
Angela M Crook, Deborah Ford, Mitzy Gafos, Richard Hayes, Anatoli Kamali, Saidi Kapiga, Andrew Nunn, Maureen Chisembele, Gita Ramjee, Helen Rees, Sheena McCormack
发表日期
2014/8/1
期刊
Human reproduction
卷号
29
期号
8
页码范围
1810-1817
出版商
Oxford University Press
简介
STUDY QUESTION
Do injectable and oral contraceptives increase the risk of human immunodeficiency virus (HIV) acquisition in women?
SUMMARY ANSWER
After adjusting for confounders, evidence of a significantly increased risk of HIV remained for women using injectable depo-medroxyprogesterone (DMPA) (hazard ratio = 1.49, 95% confidence interval (1.06–2.08)) but not for injectable norethisterone-enanthate (Net-En) or oral contraceptive pills (OC).
WHAT IS KNOWN ALREADY
An association between the use of some types of hormonal contraception (HC) methods and an increased risk of HIV, possibly through changes in the genital tract environment and alterations in the immune response, has been previously observed, although not consistently. A recent systematic review of these studies has highlighted the need for more definitive evidence …
学术搜索中的文章
AM Crook, D Ford, M Gafos, R Hayes, A Kamali… - Human reproduction, 2014