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We report on the fabrication and electrical transport properties of gate-tunable superconducting quantum interference devices (SQUIDs), made from a semiconducting PbS nanowire contacted with PbIn superconducting electrodes. With a magnetic field applied perpendicular to the plane of the nanohybrid SQUID, periodic oscillations of the critical current due to the flux quantization in SQUID are observed up to T= 4.0 K. A nonsinusoidal current–phase relationship is obtained as a function of temperature and gate voltage, which is consistent with a short and diffusive junction model.