作者
Hamid Pajavand, Amirhooshang Alvandi, Parviz Mohajeri, Somaye Bakhtyari, Homayoon Bashiri, Behnam Kalali, Markus Gerhard, Farid Najafi, Ramin Abiri
发表日期
2015/11
期刊
Jundishapur journal of microbiology
卷号
8
期号
11
出版商
Brieflands
简介
Background:
Helicobacter pylori infection and related diseases outcome are mediated by a complex interplay between bacterial, host and environmental factors. Several distinct virulence factors of H. pylori have been shown to be associated with different clinical outcomes. Here we focused on vacA and cagA genotypes of H. pylori strains isolated from patients with gastric disorder.
Objectives:
The aim of this study was to determine the frequency of two toxins and genotypes of VacA toxin in patients referred to a central hospital in the west of Iran (Imam Reza hospital, Kermanshah) during 2011-2012.
Patients and Methods:
Samples were collected from patients infected with H. pylori. Gastric biopsy specimens from the stomach antrum and corpus were cultured. PCR analysis was performed for genotyping H. pylori vacA and cagA genes.
Results:
Helicobacter pylori was isolated from 48%(96/200) of patients with …
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H Pajavand, A Alvandi, P Mohajeri, S Bakhtyari… - Jundishapur journal of microbiology, 2015