作者
Chaoran Ma, Muzi Na, Samantha Neumann, Xiang Gao
发表日期
2019/12
来源
Current atherosclerosis reports
卷号
21
页码范围
1-8
出版商
Springer US
简介
Purpose of Review
To systematically examine the association between low-density lipoprotein cholesterol (LDL-C) and risk of hemorrhagic stroke.
Recent Findings
A previous meta-analysis of prospective studies published in 2013 showed that higher concentrations of LDL-C were associated with lower risk of hemorrhagic stroke. Recently, seven large cohort studies were published examining LDL-C and risk of hemorrhagic stroke in different populations.
Summary
Twelve prospective studies with 476,173 participants and 7587 hemorrhagic stroke cases were included in the current meta-analysis. The results showed that a 10 mg/dL increase in LDL-C was associated with 3% lower risk of hemorrhagic stroke (pooled relative risk [RR] 0.97, 95% confidence interval [CI] 0.95–0.98). The association appeared to be more pronounced in Asians (pooled RR 0.95, 95% CI 0.92–0.98), relative to Caucasians (pooled RR …
学术搜索中的文章
C Ma, M Na, S Neumann, X Gao - Current atherosclerosis reports, 2019