查看文章

The present study assessed the individual and combined toxicity effects of Ag- and TiO₂- nanoparticles (NPs) on Ag bioaccumulation, oxidative stress, and gill histopathology in common carp as an aquatic animal model. The 96-h acute toxicity tests showed that TiO₂NPs enhanced the toxicity of AgNPs deducted from the decreased LC₅₀ in co-exposure to these NPs. Chronic toxicity tests included a 10-day exposure and a 10-day recovery period. In most cases, histological damages were more severe in co-exposure to Ag- and TiO₂- NPs compared with the individual AgNPs however, they were reduced in some cases and also after the recovery period. In co-exposure to Ag- and TiO₂- NPs, the Ag bioaccumulation was decreased in the gills but increased in the liver and intestine compared with the singular exposure. After the recovery period, Ag bioaccumulation decreased especially in the liver. Decreased levels of …